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Poster communications

Quality control and batch release aspects of Advanced Therapy Medicinal Products

Abstract : Quality control and batch release raise specific challenges for ensuring quality and complying with regulatory requirements in order to obtain manufacturing and marketing authorizations for Advanced Therapy Medicinal Products (ATMPs). ATMPs are medicinal products based on genes, cells and tissues that have been specifically regulated in the European Union (EU) from 2007. In the guidelines on Good Manufacturing Practices (GMP) specific to ATMPs from the European Commission, specific requirements cover quality control and batch release. They are distinct from the ones than can be found in other guidelines on GMP applicable to other kinds of biological medicinal products. Through a comparative textual analysis of the GMP guidelines for biological medicinal products and ATMPs, this poster will highlight the key areas of similarities and differences. Our analysis mainly focuses on qualification and validation procedures, batch release process, quality defects and product recalls, and automated production of ATMPs. This analysis reveals why we have two different texts and whether they are based on substantial differences regarding quality control and batch release between ATMPs and other types of biological medicinal products.
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Poster communications
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https://halshs.archives-ouvertes.fr/halshs-03780272
Contributor : Aurélie Mahalatchimy Connect in order to contact the contributor
Submitted on : Monday, September 19, 2022 - 3:43:26 PM
Last modification on : Tuesday, September 20, 2022 - 12:11:30 PM

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EAHL 2022- Qualit control & Ba...
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  • HAL Id : halshs-03780272, version 1

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Julie Veran, Michael Morrison, Florence Sabatier, Léa Chey, Fatou Mbodj, et al.. Quality control and batch release aspects of Advanced Therapy Medicinal Products. Annual Conference of the European Association of Health Law (8th EAHL-Conference), Apr 2022, Ghent, Belgium. ⟨halshs-03780272⟩

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