HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

C−Boron Enolates Enable Palladium Catalyzed Carboboration of Internal 1,3‐Enynes

Abstract : A new family of carbon-bound boron enolates, generated by a kinetically controlled halogen exchange between chlorocatecholborane and silylketene acetals, is described. These C−boron enolates are demonstrated to activate 1,3-enyne substrates in the presence of a Pd0/Senphos ligand complex, resulting in the first examples of a carboboration reaction of an alkyne with enolate-equivalent nucleophiles. Highly substituted dienyl boron building blocks are produced in excellent site-, regio-, and diastereoselectivity by the described catalytic cis-carboboration reaction.
Document type :
Journal articles
Complete list of metadata

Contributor : Karinne Miqueu Connect in order to contact the contributor
Submitted on : Wednesday, September 22, 2021 - 12:14:54 PM
Last modification on : Friday, February 11, 2022 - 3:02:01 PM
Long-term archiving on: : Thursday, December 23, 2021 - 6:35:57 PM


 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : 2022-09-22

Please log in to resquest access to the document




Ziyong Wang, Jason Wu, Walid Lamine, Bo Li, Jean-Marc Sotiropoulos, et al.. C−Boron Enolates Enable Palladium Catalyzed Carboboration of Internal 1,3‐Enynes. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, 60 (39), pp.21231-21236. ⟨10.1002/anie.202108534⟩. ⟨hal-03351154⟩



Record views