Cold Atmospheric Plasmas in interactions with materials and liquids for biological applications

Franck Clement (1) , Bernard Held , Kristacq Gazeli , Laurent Marlin (2) , Erwan Morel , Fanny Girard-Sahun , Sylvie Blanc (1) , Bruno Grassl (1) , Stephanie Reynaud (1) , Pierre Marcasuzaa , Cloé Veclin , Seif El Islam Lebouachera , Frédéric Léonardi (1) , Quentin Hoqui , Corinne Nardin (1) , Xavier Callies , Stéphane Arbault , Vasilica Badets , Pauline Lefrançois

1 IPREM - Institut des sciences analytiques et de physico-chimie pour l'environnement et les materiaux
2 UPPA - Université de Pau et des Pays de l'Adour

Cold Atmospheric Plasmas (CAPs) are now currently used for numerous applications concerning the surface treatment of solid materials at the macro-, micro- and nano- scales. Surface modifications produced lead to new functionnalities induced by the interactions of the materials with the different energy components (electrons, ions, photons, reactive species) of these partially ionised gases, produced at atmospheric pressure and temperature closed to the room one. Another large area of applications is related to the treatment of liquids in which it is possible to increase the chemical reactivity, thus allowing nanoparticles synthetisis or bacterial decontamination. In this presentation we will first discuss on the physical and chemical properties of these specific plasmas. Their principles of manufacturing will be summarized and particular attentions will be indicated on the environment around the plasma-surface interaction zone. A non-exhaustive state of the art will provide a better understanding of the physical mechanisms associated with their propagation up to the material to be treated. A large biological applications field will be then shown, illustrated by the analyses of modifications produced on steels, polymers but also on physiological liquids and living cells. Methods of the interactions characterizations are numerous and we will present some known techniques but with an innovative approach as for instance the IR-ATR spectroscopy for tracking of modifications of polymers surface. The insitu electrochemistry1 has been also developed during the plasma exposure of liquids and results obtained will be given, showing that it is possible to measure very low current in the nA range and in the presence of high electric fields used for the plasma formation. Bio-chemically Reactive Oxygen and Nitrogen Species (RONS) production (H2O2, NO2-) can thus be followed and quantified, as well as the detection of short-living species.

Domains: Analytical chemistry; Theoretical and/or physical chemistry; Polymers; Material chemistry; Plasmas

Franck Clement, Bernard Held, Kristacq Gazeli, Laurent Marlin, Erwan Morel, et al.. Cold Atmospheric Plasmas in interactions with materials and liquids for biological applications. 7 th International Symposium on Surfaces and Interfaces of Biomaterials, Jul 2019, Québec, Canada. ⟨hal-02191333⟩