Metals and biomolecules - Bioinorganic analytical chemistry
Résumé
Bioinorganic trace analytical chemistry is a rapidly developing field of research at the interface of trace element analysis and analytical biochemistry, it targets the detection, identification and characterization of substrates and products of reactions of trace metals and metalloids with the components of living cells and tissues. Hyphenated techniques based on the coupling of a separation technique (HPLC or CZE) with ICP-MS or ESI- MS/MS are becoming a fundamental tool for the functional characterization of trace elements or otherwise inconspicuous metal ions in biological systems.